468 Krušič, v. RMZ-M&G 2010, 57 sponse on the critical spot is elasto-plastic and is defined by kinematic and isotropic hardening and damage development D (2) where E stands for the elastic module, n is a Poisson ratio, s e is an effective stress, s kk is a spherical stress tensor and α(p)a function, which defines be.

The recipe for Thuringian bratwurst, as enjoyed by Goethe, is 600 years old. But aside from the pork, marjoram, caraway and garlic, the full recipe remains a closely guarded secret among the 3,000 or so Thuringian butchers. All we do know is that the sausages have to be cooked over hot charcoal and weigh around 150g.

Thuringia's ultimate fast food simply has to be accompanied by authentic Thuringian mustard. At Germany's first bratwurst museum, in Arnstadt, you can see the earliest known documentation of bratwurst, which dates from 1404. Further information about newsletter sign-up: This newsletter is a free service from Destination Germany. We will tell you about the latest offers, events, new features on our website and up-to-date reports on Destination Germany. Our newsletter may contain links to external websites run by our partners in the tourism industry, and they may use tracking tools.

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The study -- the first trial to publish five-year results from SBRT treatment for prostate cancer -- found a 98.6 percent cure rate with SBRT, a noninvasive form of radiation treatment that involves high-dose radiation beams entering the body through various angles and intersecting at the desired target. It is a state-of-the-art technology that allows for a concentrated dose to reach the tumor while limiting the radiation dose to surrounding healthy tissue. 'The high cure rate is striking when compared to the reported five-year cure rates from other approaches like surgery or conventional radiation, which range between 80 to 90 percent, while the side effects of this treatment are comparable to other types of treatment,' said Dr. Raquibul Hannan, Assistant Professor of Radiation Oncology and lead author for the study. 'What we now have is a more potent and effective form of completely noninvasive treatment for prostate cancer, conveniently completed in five treatments.'

Conventional treatment options for early stage prostate cancer include: • Prostatectomy, the surgical removal of the prostate gland, which can be done with minimally invasive techniques and robotic assistance; • Brachytherapy, in which doctors implant numerous small radioactive seeds about the size of a grain of rice into the prostate gland using multiple large needles inserted through the skin in the operating room. Once implanted, the seeds release their radioactivity directly into the prostate gland; and • External beam radiation, which involves 42 to 45 treatments administered over two or more months, five days a week. 'The current form of radiation is 44 treatments given over nine weeks.

In contrast, the SBRT therapy we used allows the delivery of highly focused radiation in only five treatments, allowing patients to return to their normal lives more quickly,' said senior author Dr. Robert Timmerman, Director of the Annette Simmons Stereotactic Treatment Center at UT Southwestern, and Professor and Vice Chairman of the Department of Radiation Oncology. 'SBRT is both more convenient and has increased potency.' UT Southwestern served as the lead site for the multi-institutional clinical trial, which involved first-time prostate cancer patients diagnosed with stage I or stage II (low and intermediate risk) prostate cancer. A total of 91 patients were treated prospectively and followed for five years, with only one patient experiencing a recurrence of his cancer. The findings are published in the European Journal of Cancer.